
In brief
- Researchers from WashU posed as prospective clients to contact 15 of the 22 active psilocybin centers in Oregon.
- All centers inquired about psychiatric history and medication; none permitted unsupervised use or offered take-home psilocybin.
- The median session cost $1,900, and no center accepted health insurance.
Oregon was the first U.S. state to regulate psilocybin with professional accompaniment. A team from Washington University in St. Louis (WashU) and the University of Missouri set out to test a practical question: what happens when someone calls one of these centers to ask if they are a candidate? The answer, published in Health Affairs Scholar, is that the screening process was more detailed than the authors themselves expected.
A mystery shopper method
The design mirrors methods used to evaluate retail or service businesses: following the path of a real client, starting with the center’s website and moving to a phone call. Three of the co-authors conducted scripted calls, posing as individuals with depression and, depending on the scenario, a history of alcohol use disorder or a family member with psychosis. They recorded whether staff asked about medication, suicidal ideation, and psychiatric history, and what price they were quoted.
Of the 26 licensed centers in Oregon, 4 had closed before the study began, leaving 22 active. The team successfully spoke with 15; the other 7 could not be reached. They also interviewed center staff regarding operating costs and licensing.
What they found
All centers complied with state legal requirements regarding screening and service delivery. None permitted unsupervised use or offered psilocybin to go. Staff routinely asked about psychiatric history, medications, and contraindications before making any recommendations, and almost all identified psychoactive drugs that should not be combined with psilocybin. None advised those taking antidepressants to stop without first consulting their primary care physician.
Kevin Xu, senior co-author of the study, noted that he expected a model similar to a dispensary—with minimal filtering—and was surprised by the thoroughness of the questions. The other senior co-author, Leopoldo Cabassa, described conversations where facilitators went beyond a simple checklist to understand the person’s history.
The flip side is the price. The median session cost $1,900, and no center accepted insurance. The staff interviewed attributed part of that cost to operating expenses and maintaining licenses, which the authors suggest makes it difficult for centers to be sustainable and for clients to afford them. Lead author Dani Adams summarized that access remains out of reach for most of those who might need it.
What it implies
For those following the regulatory debate, the study provides a useful data point: a state framework with clear screening rules can translate into consistent practices, at least in phone interactions. It also highlights the underlying tension in any regulated model, as safety guarantees cost money, and that cost is borne by the user.
It is worth reading the study with its limitations in mind. It covers only one state, 15 centers reached by phone, and scripted scenarios, meaning it measures what is said in a conversation rather than what happens during a session or the clinical outcomes. Those aspects have been addressed in other works, such as the one we covered regarding the results of legal psilocybin in Oregon. To understand what this substance is and how it acts, you can visit our page on psilocybin and magic mushrooms. According to the WashU release, the work was funded by NIH grants and university funds, with no intervention from the funders in the study.
Source
- Adams D. et al. “Am I a candidate for magic mushrooms?” A mystery shopper study of Oregon psilocybin service centers (WashU Medicine press release). Health Affairs Scholar, DOI 10.1093/haschl/qxag231, October 12, 2026.
Educational content written from a harm reduction perspective and with respect for individual freedom. It is not a substitute for advice from a healthcare professional and is not intended to encourage or condemn any drug use.