Start here · since 1996
Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

Explore the GuideAsk Noosphere

Featured articles

Explore the largest archive on psychoactive substances, published since 1996
News

Psilocybin for Persistent Lyme: A 20-Patient Pilot Study

Psiconáutica Editorial Team · October 7, 2026 In briefAn open-label pilot study at Johns Hopkins provided two psilocybin sessions to 20 people with persistent symptoms...
Read More
News

Delaware Regulates Harm Reduction and Decriminalizes Drug Paraphernalia

Psiconáutica Editorial Team · October 7, 2026 In briefThe Governor of Delaware has signed SB 249, establishing a state licensing system for harm reduction programs.The...
Read More

Mind & Spirit

Inspiring reads for open minds
Load more

From our readers

Articles chosen by our community of readers

Send us your story and get featured on our homepage

Contact us
Psychonautics

Sacred Plants and Ethnomedicine: From Kava to Iboga

An educational overview of traditional ethnomedicinal uses of sacred plants—kava, iboga, San Pedro, salvia—analyzing chemistry and clinical evidence.
Read More
Psychonautics

Cebil and Yopo: The Seeds of Bufotenine

Cebil and yopo contain bufotenine, a visionary entheogen used across South America for millennia. History, tryptamine chemistry, effects, and critical appraisal.
Read More
Psychonautics

Alexander Shulgin: The Chemist Who Mapped the Mind

A portrait of Alexander Shulgin (1925–2014), the chemist who characterized MDMA and created 2C-B, and the legacy he left in psychedelic research.
Read More
News

Fuerteventura and Psychedelic Therapy: From Enthusiasm to Caution

An international gathering in Fuerteventura brought together experts in psychedelic-assisted therapy. We explore its promises, limits, and the need for caution.
Read More
Psychonautics

Albert Hofmann and Ergot: The Origins of LSD

Albert Hofmann, the lysergic grandfather and pioneering researcher who opened up a new world through his serendipitous discovery, passed away on April 29, 2008, to embark on his final journey—just days after the sixty-fifth anniversary of his famous bicycle ride under the influence of LSD on April 19, 1943, the first acid trip in history.

Read More

News

The latest from the psychedelic world
Load more

Latest articles

Browse our most recent articles
123...78Page 2 of 78