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Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

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Explore the largest archive on psychoactive substances, published since 1996

Psilocybin for Persistent Lyme: A 20-Patient Pilot Study

Psiconáutica Editorial Team · October 7, 2026 In briefAn open-label pilot study at Johns Hopkins provided two psilocybin sessions to 20 people with persistent symptoms...

Delaware Regulates Harm Reduction and Decriminalizes Drug Paraphernalia

Psiconáutica Editorial Team · October 7, 2026 In briefThe Governor of Delaware has signed SB 249, establishing a state licensing system for harm reduction programs.The...

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Getting High on Batteries: Anatomy of an Urban Legend

In 2009, an alarm was raised: teenagers were allegedly snorting battery acid. We examine the origin of this hoax and why it doesn't hold up.

Wild Psychoactive Plants of the Iberian Peninsula (Part 1)

A botanical and critical overview of Iberian wild psychoactive plants: ephedra, opium poppy, wild lettuce, Syrian rue, and khat, with safety warnings.

The Shadow of the Stimulant: Methamphetamine and Europe’s New Challenges

An analysis of methamphetamine expansion across Europe, covering history, health risks, illicit economics, and harm reduction strategies.

“Cannabis: Avoiding Distress or Learning to Face It?”

A psychological look at cannabis between avoidance and exposure: why it calms anxiety and why it falls short as an exclusive coping strategy.

When Crack Replaces Heroin in Madrid

Why freebase has cornered heroin in Madrid’s toughest drug market—economic factors, market shifts, and a harm reduction perspective.

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