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Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

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Psilocybin and Methamphetamine: How Brain Networks Reorganize

Psiconáutica Editorial Team · October 9, 2026 In briefA functional magnetic resonance imaging (fMRI) study compares the brains of people with methamphetamine use disorder before...
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Common Drug Causes False-Positive MDMA Urine Test

Psiconáutica Editorial Team · October 9, 2026 In briefThree patients admitted in Algiers tested positive for MDMA on a rapid urine screen despite no consumption;...
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Psychonautics

Psychedelic Visions and the Brain: Beyond Huxley

Where do visions from ayahuasca or LSD originate? We examine the reducing valve hypothesis, the 5-HT2A receptor, and neuroimaging findings.
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Psychonautics

Crack and Freebase Cocaine (Part II): Risks and Harm Reduction

Continuation of the article on freebase cocaine. Read part 1.

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Psychonautics

DMT and Psychedelics: The Science That Prohibition Silenced

A review of the scientific history of psychedelics: from mescaline and LSD to biological psychiatry and the 1970 ban that halted it all.
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Psychonautics

Regulating Drugs (Part 5): Demand, Home Cultivation, and Prevention

Part five of our drug regulation model: demand management, home cultivation, consumption spaces, and evidence-based prevention.
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Psychonautics

Hashish Adulterants: What Do Laboratory Tests Actually Reveal?

Suspicions regarding the composition of cannabis from the illicit market are rampant. There are many testimonies, rumors, and tales—and many, varied adulterants that dealers are said to use to "enrich" hashish.
 
 
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