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Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

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Explore the largest archive on psychoactive substances, published since 1996

LSD Accelerates Brain Rhythms and Increases Neural Complexity

Psiconáutica Editorial Team · October 8, 2026 In briefA magnetoencephalography (MEG) reanalysis of 17 volunteers indicates that LSD accelerates the brain’s alpha and beta rhythms,...

Canada Launches New Controlled Substances Regulations for Psilocybin

Psiconáutica Editorial Team · October 8, 2026 In briefOn October 1, 2026, Canada’s new Controlled Substances Regulations went into effect, consolidating several previous rules into...

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Duto and Kisha: Heroin and Cocaine in 20th-Century Madrid

How the illicit heroin and cocaine market in Madrid evolved, from its sales points to consumption habits between the 1970s and 2000s.

Adrenochrome: From Conspiracy Myth to Real Science

What is real about adrenochrome? We separate Illuminati and reptilian myths from the actual psychiatric hypotheses of Abram Hoffer and Humphry Osmond.

LSD: Acute Effects, Pharmacological Profile, and Harm Reduction

An in-depth analysis of the first modern pharmacological LSD trial: subjective effect profiles, duration, lab safety, and comparison with other psychedelics.

Sustainable Hedonism (Part 7): Safer Drugs and Destigmatizing Users

Concluding the Sustainable Hedonism series: redirecting science toward safer consumption and normalizing the social status of people who use drugs.

Opium and Coffee: The History of Smart Drugs in Europe

A journey through opium and coffee as substances that shaped European creativity. Includes historical analysis, harm reduction, and cultural context.

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