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Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

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Explore the largest archive on psychoactive substances, published since 1996

LSD Accelerates Brain Rhythms and Increases Neural Complexity

Psiconáutica Editorial Team · October 8, 2026 In briefA magnetoencephalography (MEG) reanalysis of 17 volunteers indicates that LSD accelerates the brain’s alpha and beta rhythms,...

Canada Launches New Controlled Substances Regulations for Psilocybin

Psiconáutica Editorial Team · October 8, 2026 In briefOn October 1, 2026, Canada’s new Controlled Substances Regulations went into effect, consolidating several previous rules into...

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Cannabis and Psychosis: What the Evidence Says

Can cannabis cause psychosis? We review acute effects, epidemiological data, and the limits of causality with a critical, harm-reduction lens.

The Risk of a Psychedelic Theocracy: Mysticism vs. Rigorous Science

An analysis of how the obsession with mystical experiences in psychedelic research may be biasing scientific results and limiting progress.

Amanita, Psilocybe, and San Pedro: The Psychoactive Iberian Peninsula

A botanical and harm reduction guide to Amanita muscaria, psilocybin mushrooms, and San Pedro cacti naturalized in the Iberian Peninsula.

Albert Hofmann: The Chemist Who Sought a Medicine for the Soul

His heart stopped beating on April 29, 2008, at the age of 102, but he carried millennia of knowledge in his wake. Hofmann synthesized LSD and was the first to experience its effects. Throughout his life, he enjoyed robust health and the prestige of a visionary across various fields of science and the arts.

LSD, the medicine of Dr. Albert Hofmann

Ketamine Risks: Cystitis, Dependence, and the K-Hole

Recreational ketamine use is associated with cystitis, kidney damage, dependence, and extreme dissociation (the "K-hole"). Real risks and harm reduction.

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