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Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

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Explore the largest archive on psychoactive substances, published since 1996

LSD Accelerates Brain Rhythms and Increases Neural Complexity

Psiconáutica Editorial Team · October 8, 2026 In briefA magnetoencephalography (MEG) reanalysis of 17 volunteers indicates that LSD accelerates the brain’s alpha and beta rhythms,...

Canada Launches New Controlled Substances Regulations for Psilocybin

Psiconáutica Editorial Team · October 8, 2026 In briefOn October 1, 2026, Canada’s new Controlled Substances Regulations went into effect, consolidating several previous rules into...

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LSD and Music: Science, Perception, and Harm Reduction

A scientific review of how LSD amplifies emotional responses to music, actual pharmacokinetics, fMRI imaging studies, and clinical safety considerations.

Salvia divinorum: Real Risks and Harm Reduction Essentials

What is Salvia divinorum, how does salvinorin A act on the brain, what are the real risks, and what are the harm reduction guidelines?

Mandrake, Lotus, and Lettuce: Psychoactives in Pharaonic Egypt

An ethnobotanical exploration of mandrake, blue lotus, wild lettuce, beer, and wine in ancient Egypt, examining ritual iconographies and historical facts.

Cannabis, Emotions, and Daily Conflicts (Part II)

How to determine if a daily conflict is real, the roles of empathy and emotional coupling, and why cannabis requires caution when assessing situations.

Ketamine Risks: Cystitis, Dependence, and the K-Hole

Recreational ketamine use is associated with cystitis, kidney damage, dependence, and extreme dissociation (the "K-hole"). Real risks and harm reduction.

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