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Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

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Psilocybin for Persistent Lyme: A 20-Patient Pilot Study

Psiconáutica Editorial Team · October 7, 2026 In briefAn open-label pilot study at Johns Hopkins provided two psilocybin sessions to 20 people with persistent symptoms...
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Delaware Regulates Harm Reduction and Decriminalizes Drug Paraphernalia

Psiconáutica Editorial Team · October 7, 2026 In briefThe Governor of Delaware has signed SB 249, establishing a state licensing system for harm reduction programs.The...
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Psychonautics

The Crystal Deception: Meth Sold as Ecstasy in Spain

Discover why methamphetamine is often sold as ecstasy in Spain. We analyze the risks, pharmacological differences, and how to protect your health.
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Psychonautics

DESOXY: The Shulgin Account of Emotional Blunting

We revisit Ann Shulgin’s experience with DESOXY: a rare case of affective flattening and cold detachment, viewed through a harm reduction lens.
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Medicine and Pharmacology

Aspirin or White Willow? The Truth About Common Painkillers

Who hasn't taken an aspirin? For a headache, the flu, or a common cold, we have all swallowed a pill or sipped an effervescent aspirin at some point. This substance is so everyday and ubiquitous that few know its true name, and almost no one considers it a drug.

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Psychonautics

Cannabis Adulterants: What Forensic Lab Analyses Actually Reveal

Part two of our article on cannabis adulterants. Read part one.

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Psychonautics

Cannabis and Meditation: Examining the Content-Free Mind

Can meditation and cannabis lead to a thought-free mind? A sober examination of the content-free state, its limits, and its risks.
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