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Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

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Psilocybin for Persistent Lyme: A 20-Patient Pilot Study

Psiconáutica Editorial Team · October 7, 2026 In briefAn open-label pilot study at Johns Hopkins provided two psilocybin sessions to 20 people with persistent symptoms...
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Delaware Regulates Harm Reduction and Decriminalizes Drug Paraphernalia

Psiconáutica Editorial Team · October 7, 2026 In briefThe Governor of Delaware has signed SB 249, establishing a state licensing system for harm reduction programs.The...
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Psychonautics

Adrenochrome: From Conspiracy Myth to Real Science

What is real about adrenochrome? We separate Illuminati and reptilian myths from the actual psychiatric hypotheses of Abram Hoffer and Humphry Osmond.
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Psychonautics

Plants That Promise a High and Deliver Nothing: Debunking Myths

A critical review of plants sold as aphrodisiacs, tonics, or cannabis substitutes whose psychoactive effects are nonexistent or imperceptible.
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Psychonautics

The Shadow of the Stimulant: Methamphetamine and Europe’s New Challenges

An analysis of methamphetamine expansion across Europe, covering history, health risks, illicit economics, and harm reduction strategies.
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Psychonautics

Alexander Shulgin: The Chemist Who Mapped the Mind

A portrait of Alexander Shulgin (1925–2014), the chemist who characterized MDMA and created 2C-B, and the legacy he left in psychedelic research.
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Psychonautics

Recreational vs. Clinical Ketamine: Uses and Harm Reduction

What separates supervised clinical ketamine from recreational use: mechanisms, EMA and FDA-approved indications, bladder and kidney risks, and harm reduction.
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