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Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

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Explore the largest archive on psychoactive substances, published since 1996

Heroin and Heartbreak: Eduardo Hidalgo’s Stigma-Free Memoir

Eduardo Hidalgo releases a memoir through Autsaider Cómics detailing nearly forty years of heroin use. A guilt-free testimony that challenges the only narrative society accepts about this substance.

MDMA comedown: what a survey of 497 people found

In a cross-sectional survey of 497 people with MDMA experience, 74.5% reported negative aftereffects at least once. This self-reported sample does not establish causality, represent all users or demonstrate that supplements or antidepressants are effective for managing comedowns.

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Sobria Ebrietas: Escohotado on the History of Intoxication

An article by the master Escohotado on prohibitionism and its historical antecedents.

“DMT: The Tryptamine Within Us”

From Amazonian brews to Szára and Strassman: what we know about DMT, why the body produces it, and where data ends and mythology begins.

Albert Hofmann and LSD: Life and Legacy of the Swiss Chemist

Some individuals shape history, and Albert Hofmann was one of them. Without him, the 20th century would have been unrecognizable. Can we imagine it without psychopharmacology, the joyful—and sometimes wild—sixties, the hippies, psychedelic music, countercultural movements, alternative art, or substances like LSD and psilocybin? Our good doctor directly or indirectly influenced all those historical milestones that, in turn, continue to resonate today.

Ergot: From Medieval Poison to Hofmann’s LSD

In this final installment, we conclude the history of ergot, building on the work of Albert Hofmann. Moving forward, we will present a series of the good doctor's writings, previously unpublished in Spanish.

Bena-Riamba: The Sons of Hemp in 19th-Century Congo

In the mid-19th century, Bantu tribes in the Congo basin established a pacifist religious order centered on collective cannabis use. History and critical appraisal.

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