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Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

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Psilocybin for Persistent Lyme: A 20-Patient Pilot Study

Psiconáutica Editorial Team · October 7, 2026 In briefAn open-label pilot study at Johns Hopkins provided two psilocybin sessions to 20 people with persistent symptoms...
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Delaware Regulates Harm Reduction and Decriminalizes Drug Paraphernalia

Psiconáutica Editorial Team · October 7, 2026 In briefThe Governor of Delaware has signed SB 249, establishing a state licensing system for harm reduction programs.The...
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Psychonautics

‘LSD: My Problem Child – Albert Hofmann’s Preface’

'LSD: My Problem Child, Albert Hofmann's preface on inner experiences that escape rational explanation and transform our perception of reality.'
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Psychonautics

Hofmann and Huxley: LSD Between Serendipity and Vision

Albert Hofmann recounts the discovery of LSD and his personal friendship with Aldous Huxley, examined through historical context and critical reflection.
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Psychonautics

Drugs and Literature: Creation in Altered States

From romantic opium eaters to the French Decadents and the Beat Generation: how psychoactive substances influenced modern Western literature.
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Psychonautics

“The Celtic Pharmacopeia: Mushrooms, Nightshades, and Hemp”

The Celtic people originated in the Eurasian steppes some 3,000 years ago and spoke an Indo-European language. During the 6th century BCE, the Celts reached Galicia and Portugal, later penetrating Navarre and Aragon. The Celtic people never formed an empire, but established themselves in confederations of tribes. Their civilization flourished between the 4th and 3rd centuries BCE.

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Psychonautics

“Entheogen or Hallucinogen: Bouso and the Shaman Myth”

Bouso challenges the term "entheogen," favors "hallucinogen," debunks the myth of the idealized shaman, and reviews his ayahuasca research.
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