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Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

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Explore the largest archive on psychoactive substances, published since 1996

Heroin and Heartbreak: Eduardo Hidalgo’s Stigma-Free Memoir

Eduardo Hidalgo releases a memoir through Autsaider Cómics detailing nearly forty years of heroin use. A guilt-free testimony that challenges the only narrative society accepts about this substance.

MDMA comedown: what a survey of 497 people found

In a cross-sectional survey of 497 people with MDMA experience, 74.5% reported negative aftereffects at least once. This self-reported sample does not establish causality, represent all users or demonstrate that supplements or antidepressants are effective for managing comedowns.

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Psychedelic Psychotherapy Examined: What Does Evidence Say?

We critically examine clinical trials of psilocybin and LSD in terminal illness: modest outcomes contrasting with euphoric media headlines.

Harm Reduction: Between Scientific Evidence and Political Rhetoric

A critical analysis of how public health harm reduction strategies face sensationalist headlines, statistical ignorance, and polarization.

Dutch Coffee Shops: The Back Door Dilemma

An in-depth analysis of the Dutch coffee shop model, examining retail tolerance, wholesale prohibition, the back-door dilemma, and regulatory challenges.

Adrenochrome: The Psychedelic Myth vs. Real-World Experiences

User forums and Erowid show adrenochrome causes very mild or negligible effects, far from the myth in Fear and Loathing in Las Vegas.

“Peter Tosh: A Guitar as a Rifle Against Babylon”

At the last High Times Cannabis Cup, there was one figure whom virtually every event revolved around, directly or indirectly: Winston Hubert McIntosh, better known as Peter Tosh (10/19/1944 – 9/11/1987).

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