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Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

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Explore the largest archive on psychoactive substances, published since 1996

Psilocybin for Persistent Lyme: A 20-Patient Pilot Study

Psiconáutica Editorial Team · October 7, 2026 In briefAn open-label pilot study at Johns Hopkins provided two psilocybin sessions to 20 people with persistent symptoms...

Delaware Regulates Harm Reduction and Decriminalizes Drug Paraphernalia

Psiconáutica Editorial Team · October 7, 2026 In briefThe Governor of Delaware has signed SB 249, establishing a state licensing system for harm reduction programs.The...

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The Science of Aspirin and Coke: Debunking a Persistent Myth

Does it make you horny? Is it a magic aphrodisiac? We analyze the famous aspirin and Coca-Cola myth through pharmacology, history, and real risks.

We Are Standard: Danceable Pop, London, and the Cannabis Question

Basque band We Are Standard on recording with Andy Gill and Arthur Baker, and a critical look at the myth linking cannabis to musical creativity.

How Anxiety Works: The Fear That Anticipates

Anxiety as an anticipatory emotion, how it distorts attention, memory, and interpretation, and why excessive activation limits our lives.

Ibogaine and Opioids: What Science Knows About Dependency

What is known about ibogaine and interrupting opioid dependency: preliminary evidence, ongoing trials, cardiac risks, and harm reduction.

Expiration of Psychoactive Substances: Chemical Stability and Storage

An analysis of the shelf life of illicit drugs, molecular degradation processes, and the real impact of storage on potency and safety.

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