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Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

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Psilocybin and Methamphetamine: How Brain Networks Reorganize

Psiconáutica Editorial Team · October 9, 2026 In briefA functional magnetic resonance imaging (fMRI) study compares the brains of people with methamphetamine use disorder before...

Common Drug Causes False-Positive MDMA Urine Test

Psiconáutica Editorial Team · October 9, 2026 In briefThree patients admitted in Algiers tested positive for MDMA on a rapid urine screen despite no consumption;...

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Ergot: Poison, Entheogen, and Medicine

 

In previous installments, we discussed ergot, a fungus that parasitizes certain cereals and enabled the discovery of LSD and the synthesis of highly useful drugs (see Spannabis Magazine No. 51 and No. 52). Now, we will focus on botanical, medical, and pharmacological aspects, exploring how this fungus has played a starring role in various historical moments.

 

 

Coca Leaf and Ephedra: A European Legal Paradox

January 2008 marked the month when all Dutch shops pulled both dried stems of any ephedra species and any product containing ephedrine—a natural stimulant drug with effects identical to amphetamine, which chemists call deoxyephedrine—from their shelves.

The Medicinal Side of Five Psychoactive Plants

Mandrake, kratom, opium, yohimbe, and harmel: we review the traditional medicinal uses of five psychoactive plants with critical caution.

Sustainable Hedonism: From Prohibition to Pleasure Management

If skiing were persecuted like drugs, would there be fewer accidents? A critique of prohibitionism and a proposal for sustainable hedonism.

Sustainable Hedonism (Part 7): Safer Drugs and Destigmatizing Users

Concluding the Sustainable Hedonism series: redirecting science toward safer consumption and normalizing the social status of people who use drugs.

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