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Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

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Psilocybin and Methamphetamine: How Brain Networks Reorganize

Psiconáutica Editorial Team · October 9, 2026 In briefA functional magnetic resonance imaging (fMRI) study compares the brains of people with methamphetamine use disorder before...

Common Drug Causes False-Positive MDMA Urine Test

Psiconáutica Editorial Team · October 9, 2026 In briefThree patients admitted in Algiers tested positive for MDMA on a rapid urine screen despite no consumption;...

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Coca and Cocaine: A History of Power, Ritual, and Chemistry

 

The coca leaf is obtained from a shrub native to South America, specifically the warm and humid regions of the Andes (Colombia, Bolivia, and Peru). The history of coca plant use is nearly as long as humanity itself. Archaeological remains confirm its consumption in northwestern Peru as early as the sixth millennium BCE.

 

Shulgin (I): The Chemical Vocation of a Psychonaut

Biography of Alexander Shulgin, one of the most prolific figures in psychopharmacology, exploring his early life, the placebo event, and his mescaline epiphany.

Wild Lettuce and Lactucarium: The “Opium” That Wasn’t

Wild lettuce (Lactuca virosa) and its latex, lactucarium, once promised dreams and mild sedation. We review the history, science, and risks.

Master Plants and Their Disciples

by Jean-Pierre Chaumeil

Since 1971, Jean-Pierre CHAUMEIL, a French ethnologist, has spent several periods in the Peruvian Amazon, especially among the Yagua of the northeastern region, with whom he lived for more than three years together with his wife. His primary interest is the comparative study of shamanism and, more generally, everything surrounding the new forms of religiosity in the Amazon. He is the author of several books, among them “Voir, savoir, pouvoir” (Ed. de l’EHESS, Paris, 1983) and “Ñihamwo” (CAAAP, Lima, 1987). A research officer at the National Center for Scientific Research (CNRS), he belongs to its Amerindian Anthropology Research Team (France).

Cannabis and Creativity: Concepts, Dopamine, and Open Minds

How cannabis and creativity relate: divergent thinking, the dopamine-serotonin balance, and over-inclusion, with critical nuance.

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