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Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

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Psilocybin and Methamphetamine: How Brain Networks Reorganize

Psiconáutica Editorial Team · October 9, 2026 In briefA functional magnetic resonance imaging (fMRI) study compares the brains of people with methamphetamine use disorder before...
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Common Drug Causes False-Positive MDMA Urine Test

Psiconáutica Editorial Team · October 9, 2026 In briefThree patients admitted in Algiers tested positive for MDMA on a rapid urine screen despite no consumption;...
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Psychonautics

Cultivating Psilocybe cubensis: Biology, Culture, and Risks

What lies behind the home cultivation of Psilocybe cubensis: its biology, the legal context in Spain, and a critical look from a harm reduction perspective.
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Psychonautics

Why Marijuana Is Illegal: The History of Prohibition

From mandatory crop to contraband plant: an objective historical account of how cannabis was criminalized in the United States and the corporate interests involved.
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Psychonautics

“Alexander Shulgin: The Chemist Who Mapped the Mind”

"A profile of Alexander Shulgin (1925–2014), the chemist who characterized MDMA and created 2C-B, and his enduring mark on psychedelic research."
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Psychonautics

What Is Ketamine: Pharmacology, Effects, and Medical Uses

What is ketamine: how it acts on the NMDA receptor, its uses in anesthesia, pain, and depression, and the risks of non-medical use.
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Psychonautics

LSD Therapy: Why Research Actually Stalled

It wasn’t the hippie movement that stopped LSD therapy, but the 1962 clinical trial regulations and Sandoz’s withdrawal. We explain why.
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