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Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

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Psilocybin for Persistent Lyme: A 20-Patient Pilot Study

Psiconáutica Editorial Team · October 7, 2026 In briefAn open-label pilot study at Johns Hopkins provided two psilocybin sessions to 20 people with persistent symptoms...
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Delaware Regulates Harm Reduction and Decriminalizes Drug Paraphernalia

Psiconáutica Editorial Team · October 7, 2026 In briefThe Governor of Delaware has signed SB 249, establishing a state licensing system for harm reduction programs.The...
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Psychonautics

Harm Reduction: Between Scientific Evidence and Political Rhetoric

A critical analysis of how public health harm reduction strategies face sensationalist headlines, statistical ignorance, and polarization.
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Psychonautics

The HIV Syringe in the Movie Theater Seat Hoax

For decades, a rumor persisted that HIV-infected syringes were being left in movie theater seats. We examine the myth, the reality, and why it mattered.
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Psychonautics

Escohotado (I): The Philosopher, LSD, and Freak Ibiza

A biography of Antonio Escohotado covering his philosophical education, his mid-1960s initiation with LSD, and his freak period in 1970s Ibiza.
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Psychonautics

“Alexander Shulgin: The Chemist Who Mapped the Mind”

"A profile of Alexander Shulgin (1925–2014), the chemist who characterized MDMA and created 2C-B, and his enduring mark on psychedelic research."
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Psychonautics

LSD and Music: Science, Perception, and Harm Reduction

A scientific review of how LSD amplifies emotional responses to music, actual pharmacokinetics, fMRI imaging studies, and clinical safety considerations.
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