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Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

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Explore the largest archive on psychoactive substances, published since 1996

LSD Accelerates Brain Rhythms and Increases Neural Complexity

Psiconáutica Editorial Team · October 8, 2026 In briefA magnetoencephalography (MEG) reanalysis of 17 volunteers indicates that LSD accelerates the brain’s alpha and beta rhythms,...

Canada Launches New Controlled Substances Regulations for Psilocybin

Psiconáutica Editorial Team · October 8, 2026 In briefOn October 1, 2026, Canada’s new Controlled Substances Regulations went into effect, consolidating several previous rules into...

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Cannabis and Psychosis: What the Evidence Says

Can cannabis cause psychosis? We review acute effects, epidemiological data, and the limits of causality with a critical, harm-reduction lens.

Aspirin or White Willow? The Truth About Common Painkillers

Who hasn't taken an aspirin? For a headache, the flu, or a common cold, we have all swallowed a pill or sipped an effervescent aspirin at some point. This substance is so everyday and ubiquitous that few know its true name, and almost no one considers it a drug.

“Peter Tosh: A Guitar as a Rifle Against Babylon”

At the last High Times Cannabis Cup, there was one figure whom virtually every event revolved around, directly or indirectly: Winston Hubert McIntosh, better known as Peter Tosh (10/19/1944 – 9/11/1987).

Opium in Ancient Rome: Everyday Medicine of an Empire

In Rome, drugs were regulated by the Lex Cornelia, and while many substances were used, opium was the most common for pain treatment and forgetting life's troubles (Torres et al. 1997: 12).

Literary Roots of Psychedelia: From Osmond to Kerouac

Before the hippie movement and Leary, psychedelia was forged in literature. We take a critical look at Osmond, Huxley, and the Beat Generation.

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