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Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

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LSD Accelerates Brain Rhythms and Increases Neural Complexity

Psiconáutica Editorial Team · October 8, 2026 In briefA magnetoencephalography (MEG) reanalysis of 17 volunteers indicates that LSD accelerates the brain’s alpha and beta rhythms,...
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Canada Launches New Controlled Substances Regulations for Psilocybin

Psiconáutica Editorial Team · October 8, 2026 In briefOn October 1, 2026, Canada’s new Controlled Substances Regulations went into effect, consolidating several previous rules into...
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Psychonautics

Base Cocaine and Crack: What They Are and How They Differ

The dealer’s dream. The user’s nightmare. That is how many summarize the essence of the substance Americans call crack and we call base. Let’s explore some of its secrets.
 
 
 
 
 
 
 
cocainabase
 
 
 
 
 
 
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Psychonautics

Groove 3: Bassless Jazz and the Groove as Shared Trance

An archival interview with jazz trio Groove 3: their bassless Hammond organ sound, musical influences, and groove as an altered state of consciousness.
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Psychonautics

What Is Salvia Divinorum: The Mazatec Visionary Plant

What is Salvia divinorum, the Mazatec visionary plant: its history, salvinorin A, its effects, scientific research, and harm reduction practices.
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Psychonautics

“Alexander Shulgin: The Chemist Who Mapped the Mind”

"A profile of Alexander Shulgin (1925–2014), the chemist who characterized MDMA and created 2C-B, and his enduring mark on psychedelic research."
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Psychonautics

Piracetam: The Origin of Smart Drugs

Piracetam is the standard nootropic, the one we might consider the father of smart drugs. It was first synthesized in 1964 by the team led by Corneliu Giurgea at the Belgian pharmaceutical company UCB (Union Chimique Belge), which was founded in 1928 and specialized in, among other things, medications for the nervous system.

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