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Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

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LSD Accelerates Brain Rhythms and Increases Neural Complexity

Psiconáutica Editorial Team · October 8, 2026 In briefA magnetoencephalography (MEG) reanalysis of 17 volunteers indicates that LSD accelerates the brain’s alpha and beta rhythms,...

Canada Launches New Controlled Substances Regulations for Psilocybin

Psiconáutica Editorial Team · October 8, 2026 In briefOn October 1, 2026, Canada’s new Controlled Substances Regulations went into effect, consolidating several previous rules into...

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“Alexander Shulgin: The Chemist Who Mapped the Mind”

"A profile of Alexander Shulgin (1925–2014), the chemist who characterized MDMA and created 2C-B, and his enduring mark on psychedelic research."

Adrenochrome: The Psychedelic Myth vs. Real-World Experiences

User forums and Erowid show adrenochrome causes very mild or negligible effects, far from the myth in Fear and Loathing in Las Vegas.

Is Getting High Natural? What the Animal Kingdom Teaches Us

Ants, elephants, and humans all seek intoxication. We examine the idea of Siegel’s "fourth drive" and its limits with a critical eye.

Sustainable Drugophilia: Regulating Drugs Instead of Prohibition

Part three of the series: what sustainable drug use proposes and what legal drug regulation could look like instead of prohibition.

The Bwiti Ritual: Traditional Iboga Use in Gabon

Bwiti, a spiritual tradition from Gabon, uses the root of the iboga plant in its initiation rites. Here is what it is and what science says about ibogaine.

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