Start here · since 1996
Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

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Psilocybin and Methamphetamine: How Brain Networks Reorganize

Psiconáutica Editorial Team · October 9, 2026 In briefA functional magnetic resonance imaging (fMRI) study compares the brains of people with methamphetamine use disorder before...

Common Drug Causes False-Positive MDMA Urine Test

Psiconáutica Editorial Team · October 9, 2026 In briefThree patients admitted in Algiers tested positive for MDMA on a rapid urine screen despite no consumption;...

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Sulbutiamine: The Vitamin B1 Derivative Known as a Nootropic

A large portion of the world’s population uses some form of stimulant. Coffee, tea, mate, cocoa, guarana, coca leaf, ephedra, cocaine, amphetamines... The desire to feel well and experience a positive stimulation that helps us manage daily activities is practically universal.

The Amsterdam Hash Marihuana & Hemp Museum: Forgotten History

A tour through Amsterdam's Hash Marihuana & Hemp Museum and the long industrial, artistic, and medicinal history erased by modern prohibition.

“DMT: The Tryptamine Within Us”

From Amazonian brews to Szára and Strassman: what we know about DMT, why the body produces it, and where data ends and mythology begins.

Regulating Drugs: Sales, Legal Age, and Pricing Models

How would authorized sales, legal age limits, and pricing work in a regulated drug model compared to the chaos of prohibition?

Yohimbe and Yohimbine: The Aphrodisiac Science Examined

This tree, native to West Africa (Cameroon, Equatorial Guinea, Congo, etc.), is now cultivated in several African countries to satisfy the vast global demand for yohimbe bark and its derivatives, particularly herbal yohimbe extract and pure yohimbine hydrochloride.

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