Eduardo Hidalgo releases a memoir through Autsaider Cómics detailing nearly forty years of heroin use. A guilt-free testimony that challenges the only narrative society accepts about this substance.

In a cross-sectional survey of 497 people with MDMA experience, 74.5% reported negative aftereffects at least once. This self-reported sample does not establish causality, represent all users or demonstrate that supplements or antidepressants are effective for managing comedowns.

Before the hippie movement and Leary, psychedelia was forged in literature. We take a critical look at Osmond, Huxley, and the Beat Generation.

Kanna (Sceletium tortuosum) is a South African succulent used by the San and Khoikhoi. We examine its chemistry, subjective effects, and safety limits.

From its 1962 synthesis as an anesthetic to the FDA-approved esketamine for treatment-resistant depression, we explore the history of ketamine.

The second installment of our article on the positions of non-cannabis-focused political parties regarding cannabis. Read the first part.

An analysis of how the obsession with mystical experiences in psychedelic research may be biasing scientific results and limiting progress.