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Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

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LSD Accelerates Brain Rhythms and Increases Neural Complexity

Psiconáutica Editorial Team · October 8, 2026 In briefA magnetoencephalography (MEG) reanalysis of 17 volunteers indicates that LSD accelerates the brain’s alpha and beta rhythms,...
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Canada Launches New Controlled Substances Regulations for Psilocybin

Psiconáutica Editorial Team · October 8, 2026 In briefOn October 1, 2026, Canada’s new Controlled Substances Regulations went into effect, consolidating several previous rules into...
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Psychonautics

Shulgin and MDMA: From Merck’s Archives to the Personal Lab

Shulgin’s intensity scale, the long oblivion of MDMA in Merck’s archives, and its 1965 rediscovery, stripped of sensationalism.
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Psychonautics

Cannabis and Creativity: Concepts, Dopamine, and Open Minds

How cannabis and creativity relate: divergent thinking, the dopamine-serotonin balance, and over-inclusion, with critical nuance.
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Psychonautics

Crack and Freebase Cocaine (Part II): Risks and Harm Reduction

Continuation of the article on freebase cocaine. Read part 1.

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Psychonautics

Shulgin and MDMA: From the Merck Archives to the Home Lab

Shulgin’s rating scale, the long neglect of MDMA in the Merck archives, and its 1965 rediscovery, told without sensationalism.
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Psychonautics

Amanita muscaria: History and Reality of the First Entheogen

The unmistakable red mushroom with white warts appears to be the oldest visionary agent, used by Siberian peoples as far back as 6,000 to 8,000 years ago. This is evidenced by the fact that in various languages, similar words are used both to describe "intoxication" ("being fungized") and to name the mushroom itself: panx, the oldest known word for this fungus (Ott 1998).

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