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Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

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Explore the largest archive on psychoactive substances, published since 1996

Psilocybin for Persistent Lyme: A 20-Patient Pilot Study

Psiconáutica Editorial Team · October 7, 2026 In briefAn open-label pilot study at Johns Hopkins provided two psilocybin sessions to 20 people with persistent symptoms...

Delaware Regulates Harm Reduction and Decriminalizes Drug Paraphernalia

Psiconáutica Editorial Team · October 7, 2026 In briefThe Governor of Delaware has signed SB 249, establishing a state licensing system for harm reduction programs.The...

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Cannabis Adulterants: What Laboratory Tests Reveal

Reviewing laboratory data on cannabis adulteration: why commercial hashish quality is poor and what scientific drug checking reveals.

Salvia divinorum: The Visionary Plant of the Mazatecs

Everything about Salvia divinorum and salvinorin A: traditional Mazatec shamanism, kappa-opioid pharmacology, subjective effects, and harm reduction.

Burundanga: Between Media Myth and Toxicological Reality

A critical analysis of burundanga. Deconstructing myths of chemical submission and loss of free will against scientific, epidemiological, and forensic data.

Alexander Shulgin: The Chemist Who Mapped the Mind

A portrait of Alexander Shulgin (1925–2014), the chemist who characterized MDMA and created 2C-B, and the legacy he left in psychedelic research.

Cocaine Purity and Duration: Facts, Myths, and Harm Reduction

An analysis of cocaine purity, cuts, and duration of effects. Scientific facts versus street myths in the context of cocaine use.

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