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Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

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LSD Accelerates Brain Rhythms and Increases Neural Complexity

Psiconáutica Editorial Team · October 8, 2026 In briefA magnetoencephalography (MEG) reanalysis of 17 volunteers indicates that LSD accelerates the brain’s alpha and beta rhythms,...

Canada Launches New Controlled Substances Regulations for Psilocybin

Psiconáutica Editorial Team · October 8, 2026 In briefOn October 1, 2026, Canada’s new Controlled Substances Regulations went into effect, consolidating several previous rules into...

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“Selegiline: History and Promises of the MAO-B Inhibitor”

Selegiline is a drug with multiple applications belonging to the phenethylamine class—just like amphetamines, mescaline, MDMA, and other substances—that selectively and irreversibly inhibits monoamine oxidase-B, an enzyme that breaks down monoamine neurotransmitters in neurons.

If Skiing Were Illegal: A Satire on Prohibitionism

Eduardo Hidalgo imagines skiing being persecuted like drugs to expose the absurdity of prohibition and advocate for harm reduction.

LSD Therapy: Why Research Actually Stalled

It wasn’t the hippie movement that stopped LSD therapy, but the 1962 clinical trial regulations and Sandoz’s withdrawal. We explain why.

If Skiing Were Illegal: A Satire on Prohibitionism

Eduardo Hidalgo imagines skiing being persecuted like drugs to expose the absurdity of prohibition and advocate for harm reduction.

Hofmann and Huxley: LSD Between Serendipity and Vision

Albert Hofmann recounts the discovery of LSD and his personal friendship with Aldous Huxley, examined through historical context and critical reflection.

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