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Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

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LSD Accelerates Brain Rhythms and Increases Neural Complexity

Psiconáutica Editorial Team · October 8, 2026 In briefA magnetoencephalography (MEG) reanalysis of 17 volunteers indicates that LSD accelerates the brain’s alpha and beta rhythms,...

Canada Launches New Controlled Substances Regulations for Psilocybin

Psiconáutica Editorial Team · October 8, 2026 In briefOn October 1, 2026, Canada’s new Controlled Substances Regulations went into effect, consolidating several previous rules into...

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Piracetam: The Origin of Smart Drugs

Piracetam is the standard nootropic, the one we might consider the father of smart drugs. It was first synthesized in 1964 by the team led by Corneliu Giurgea at the Belgian pharmaceutical company UCB (Union Chimique Belge), which was founded in 1928 and specialized in, among other things, medications for the nervous system.

Literary Roots of Psychedelia: From Osmond to Kerouac

Before the hippie movement and Leary, psychedelia was forged in literature. We take a critical look at Osmond, Huxley, and the Beat Generation.

Sulbutiamine: The Vitamin B1 Derivative Known as a Nootropic

A large portion of the world’s population uses some form of stimulant. Coffee, tea, mate, cocoa, guarana, coca leaf, ephedra, cocaine, amphetamines... The desire to feel well and experience a positive stimulation that helps us manage daily activities is practically universal.

Cocaine Purity and Duration: Facts, Myths, and Harm Reduction

An analysis of cocaine purity, cuts, and duration of effects. Scientific facts versus street myths in the context of cocaine use.

The Amsterdam Hash Marihuana & Hemp Museum: Forgotten History

A tour through Amsterdam's Hash Marihuana & Hemp Museum and the long industrial, artistic, and medicinal history erased by modern prohibition.

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