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Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

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Explore the largest archive on psychoactive substances, published since 1996

Psilocybin for Persistent Lyme: A 20-Patient Pilot Study

Psiconáutica Editorial Team · October 7, 2026 In briefAn open-label pilot study at Johns Hopkins provided two psilocybin sessions to 20 people with persistent symptoms...

Delaware Regulates Harm Reduction and Decriminalizes Drug Paraphernalia

Psiconáutica Editorial Team · October 7, 2026 In briefThe Governor of Delaware has signed SB 249, establishing a state licensing system for harm reduction programs.The...

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Ska-P and “Cannabis”: Protest Music Against Prohibition

Thanks to an overwhelming live presence, tremendously catchy songs, and a unique musical style, Ska-P has defined an era and a place within this country’s musical history.

Sacred Plants and Ethnomedicine: From Kava to Iboga

An educational overview of traditional ethnomedicinal uses of sacred plants—kava, iboga, San Pedro, salvia—analyzing chemistry and clinical evidence.

Shulgin (I): The Chemical Vocation of a Psychonaut

Biography of Alexander Shulgin, one of the most prolific figures in psychopharmacology, exploring his early life, the placebo event, and his mescaline epiphany.

Mummies as Drugs: Anatomy of a Psychonautic Hoax

A rumor persists that mummies were consumed for their psychoactive effects. We trace the origin of this hoax: a mistranslation of "drug" as "narcotic" rather than "medicine."

The Haitian Zombie Myth: Science, Faith, and Clairvius Narcisse

An ethnobotanical analysis of the zombie phenomenon in Haiti. The case of Clairvius Narcisse, tetrodotoxin, and the sociocultural context.

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