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Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

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Explore the largest archive on psychoactive substances, published since 1996

Psilocybin and Methamphetamine: How Brain Networks Reorganize

Psiconáutica Editorial Team · October 9, 2026 In briefA functional magnetic resonance imaging (fMRI) study compares the brains of people with methamphetamine use disorder before...

Common Drug Causes False-Positive MDMA Urine Test

Psiconáutica Editorial Team · October 9, 2026 In briefThree patients admitted in Algiers tested positive for MDMA on a rapid urine screen despite no consumption;...

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Understanding Iboga: The African Shrub and Ibogaine Alkaloid

Iboga is an African shrub containing ibogaine, an alkaloid studied for addiction treatment that carries significant cardiac risks.

DESOXY: The Shulgin Account on Emotional Flattening

We revisit Ann Shulgin’s testimony on DESOXY: a case of affective flattening and cold detachment, with critical reading and harm reduction.

“The Restless Child Business: ADHD, Labels, and Pills”

The hyperactivity syndrome is in vogue. Who doesn't know a child diagnosed with ADHD taking prescription methylphenidate? At first glance, detecting and treating an illness seems positive, but reality is far more complex than it appears.

“Where Cannabis Comes From: The Equatorial African Trail”

Every grower of psychoactive cannabis has wondered at some point where the commercial strains grown today actually originate.

Cannabis and Emotional Distress: When It Becomes the Only Way Out

Cannabis can soothe the sting of life’s setbacks, but relying on it as your sole coping mechanism comes at a cost. We break it down.

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