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Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

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Explore the largest archive on psychoactive substances, published since 1996

LSD Accelerates Brain Rhythms and Increases Neural Complexity

Psiconáutica Editorial Team · October 8, 2026 In briefA magnetoencephalography (MEG) reanalysis of 17 volunteers indicates that LSD accelerates the brain’s alpha and beta rhythms,...

Canada Launches New Controlled Substances Regulations for Psilocybin

Psiconáutica Editorial Team · October 8, 2026 In briefOn October 1, 2026, Canada’s new Controlled Substances Regulations went into effect, consolidating several previous rules into...

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Cannabis and Meditation: Examining the Content-Free Mind

Can meditation and cannabis lead to a thought-free mind? A sober examination of the content-free state, its limits, and its risks.

LSD and Suggestibility: Between Therapy, Risk, and the Mind

We explore how LSD modulates suggestibility through a harm reduction lens, analyzing recent studies and the historical context of these effects.

Hofmann and Psilocybin: From Teonanácatl to the Test Tube

A new installment from the original writings of the discoverer of LSD.

Amsterdam’s Cannabis Museum: A History of the Plant

The Hash Marihuana & Hemp Museum is located in the heart of Amsterdam, right in the middle of the Red Light District (De Wallen), in the Netherlands.

Escohotado’s Letter to the Mother of a Drug Addict

An article by Antonio Escohotado: old, but as relevant as ever. And above all, a classic.

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