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Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

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Psilocybin for Persistent Lyme: A 20-Patient Pilot Study

Psiconáutica Editorial Team · October 7, 2026 In briefAn open-label pilot study at Johns Hopkins provided two psilocybin sessions to 20 people with persistent symptoms...
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Delaware Regulates Harm Reduction and Decriminalizes Drug Paraphernalia

Psiconáutica Editorial Team · October 7, 2026 In briefThe Governor of Delaware has signed SB 249, establishing a state licensing system for harm reduction programs.The...
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Psychonautics

Regulating Drugs (Part 5): Demand, Home Cultivation, and Prevention

Part five of our drug regulation model: demand management, home cultivation, consumption spaces, and evidence-based prevention.
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Psychonautics

“The Celtic Pharmacopeia: Mushrooms, Nightshades, and Hemp”

The Celtic people originated in the Eurasian steppes some 3,000 years ago and spoke an Indo-European language. During the 6th century BCE, the Celts reached Galicia and Portugal, later penetrating Navarre and Aragon. The Celtic people never formed an empire, but established themselves in confederations of tribes. Their civilization flourished between the 4th and 3rd centuries BCE.

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Psychonautics

Shulgin and the LSD Flashback Myth: What Pharmacology Says

In TIHKAL, Shulgin dismantles the myth of the LSD flashback, explaining that the molecule is eliminated in hours and memories are not latent psychosis.
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Psychonautics

Weed Fertilized with LSD: Anatomy of an Urban Legend

Can marijuana be treated with LSD or magic mushrooms to boost potency? We examine actual THC levels and why heat destroys acid.
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Psychonautics

“Alexander Shulgin: The Chemist Who Mapped the Mind”

"A profile of Alexander Shulgin (1925–2014), the chemist who characterized MDMA and created 2C-B, and his enduring mark on psychedelic research."
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