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Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

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Psilocybin for Persistent Lyme: A 20-Patient Pilot Study

Psiconáutica Editorial Team · October 7, 2026 In briefAn open-label pilot study at Johns Hopkins provided two psilocybin sessions to 20 people with persistent symptoms...
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Delaware Regulates Harm Reduction and Decriminalizes Drug Paraphernalia

Psiconáutica Editorial Team · October 7, 2026 In briefThe Governor of Delaware has signed SB 249, establishing a state licensing system for harm reduction programs.The...
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Psychonautics

Why Marijuana Is Illegal: The History of Prohibition

From mandatory crop to contraband plant: an objective historical account of how cannabis was criminalized in the United States and the corporate interests involved.
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Psychonautics

Psychedelic Medicine: A Practical Guide for Patients and Clinicians

An analysis of psychedelic medicine in Spain and Europe. MDMA, psilocybin, and ketamine: clinical evidence, regulatory frameworks, and harm reduction.
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Psychonautics

DESOXY: The Shulgin Account on Emotional Flattening

We revisit Ann Shulgin’s testimony on DESOXY: a case of affective flattening and cold detachment, with critical reading and harm reduction.
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Psychonautics

Ibogaine Legality and Clinics Worldwide: What We Know

Ibogaine shows promise in treating addiction and trauma. We review its legal status by country, the state of clinics, and associated cardiac risks.
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Psychonautics

Cannabis and Meditation: Focus, Mind, and Caution

How cannabis affects attention and why some Buddhist schools used it during meditation, with a simple exercise and critical analysis.
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