Start here · since 1996
Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

Featured articles

Explore the largest archive on psychoactive substances, published since 1996

Psilocybin for Persistent Lyme: A 20-Patient Pilot Study

Psiconáutica Editorial Team · October 7, 2026 In briefAn open-label pilot study at Johns Hopkins provided two psilocybin sessions to 20 people with persistent symptoms...

Delaware Regulates Harm Reduction and Decriminalizes Drug Paraphernalia

Psiconáutica Editorial Team · October 7, 2026 In briefThe Governor of Delaware has signed SB 249, establishing a state licensing system for harm reduction programs.The...

Mind & Spirit

Inspiring reads for open minds

From our readers

Articles chosen by our community of readers

Send us your story and get featured on our homepage

“Entheogen or Hallucinogen: Bouso and the Shaman Myth”

Bouso challenges the term "entheogen," favors "hallucinogen," debunks the myth of the idealized shaman, and reviews his ayahuasca research.

Hofmann and Huxley: LSD Between Serendipity and Vision

Albert Hofmann recounts the discovery of LSD and his personal friendship with Aldous Huxley, examined through historical context and critical reflection.

“Ibogaine and Addiction: Promises, Clinical Evidence, and Limitations”

Ibogaine is under investigation for opioid addiction. We review the clinical evidence, cardiac risks, and why it remains experimental.

The Truth About Smoking Toothpaste: Myths, Fluoride, and Science

Can smoking toothpaste get you high? Far from being a recreational drug, this habit poses a serious toxicological risk. Eduardo Hidalgo debunks urban legends about toothpaste-induced hallucinations and warns of the dangers of fluoride poisoning, urging readers to prioritize dental health instead.

Ketamine: Between Anesthesia and Neuronal Regeneration

We explore the clinical profile of ketamine, from its safety in surgery to its emerging role in treatment-resistant depression and addiction.

News

The latest from the psychedelic world

Latest articles

Browse our most recent articles