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Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

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Explore the largest archive on psychoactive substances, published since 1996

Heroin and Heartbreak: Eduardo Hidalgo’s Stigma-Free Memoir

Eduardo Hidalgo releases a memoir through Autsaider Cómics detailing nearly forty years of heroin use. A guilt-free testimony that challenges the only narrative society accepts about this substance.

MDMA comedown: what a survey of 497 people found

In a cross-sectional survey of 497 people with MDMA experience, 74.5% reported negative aftereffects at least once. This self-reported sample does not establish causality, represent all users or demonstrate that supplements or antidepressants are effective for managing comedowns.

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Hofmann and the Entheogens of Mexico: From LSD to Psilocybin

We continue our look at Albert Hofmann’s drug discoveries with another article previously unpublished in Spanish. Here, he details the relationship between LSD and entheogenic substances like teonanácatl, ololiuqui, mescaline, psilocybin, and psilocin.

LSD, the medicine of Dr. Albert Hofmann

Base Cocaine and Crack: What They Are and How They Differ

The dealer’s dream. The user’s nightmare. That is how many summarize the essence of the substance Americans call crack and we call base. Let’s explore some of its secrets.
 
 
 
 
 
 
 
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Adrenochrome: Hidalgo’s Conclusion and Lingering Scientific Questions

Eduardo Hidalgo concludes his series on adrenochrome: worthless recreationally, but displaying subtle psychotomimetic effects that psychiatry abandoned too early.

Cultivating Psilocybe cubensis: Biology, Culture, and Risks

What lies behind the home cultivation of Psilocybe cubensis: its biology, the legal context in Spain, and a critical look from a harm reduction perspective.

Dutch Coffee Shops: The Back Door Dilemma

An in-depth analysis of the Dutch coffee shop model, examining retail tolerance, wholesale prohibition, the back-door dilemma, and regulatory challenges.

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