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Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

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Psilocybin and Methamphetamine: How Brain Networks Reorganize

Psiconáutica Editorial Team · October 9, 2026 In briefA functional magnetic resonance imaging (fMRI) study compares the brains of people with methamphetamine use disorder before...
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Common Drug Causes False-Positive MDMA Urine Test

Psiconáutica Editorial Team · October 9, 2026 In briefThree patients admitted in Algiers tested positive for MDMA on a rapid urine screen despite no consumption;...
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Psychonautics

Cannabis and the Big Five: Does It Modulate Personality?

We review the Big Five personality traits and the idea that cannabis modulates traits like extraversion or neuroticism, with a critical eye.
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Psychonautics

Shulgin and MDMA: From the Merck Archives to the Home Lab

Shulgin’s rating scale, the long neglect of MDMA in the Merck archives, and its 1965 rediscovery, told without sensationalism.
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Psychonautics

Cannabis and Meditation: Focus, Mind, and Caution

How cannabis affects attention and why some Buddhist schools used it during meditation, with a simple exercise and critical analysis.
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Psychonautics

Cannabis and Creativity: Concepts, Dopamine, and Open Minds

How cannabis and creativity relate: divergent thinking, the dopamine-serotonin balance, and over-inclusion, with critical nuance.
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Psychonautics

Mummies as Drugs: Anatomy of a Psychonautic Hoax

A rumor persists that mummies were consumed for their psychoactive effects. We trace the origin of this hoax: a mistranslation of "drug" as "narcotic" rather than "medicine."
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