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Psychedelics Guide

More than 500 articles organized by substance and topic: psilocybin, LSD, ayahuasca, DMT, MDMA, mescaline and harm reduction. Rigorous information, without fear and without propaganda.

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Explore the largest archive on psychoactive substances, published since 1996

LSD Accelerates Brain Rhythms and Increases Neural Complexity

Psiconáutica Editorial Team · October 8, 2026 In briefA magnetoencephalography (MEG) reanalysis of 17 volunteers indicates that LSD accelerates the brain’s alpha and beta rhythms,...

Canada Launches New Controlled Substances Regulations for Psilocybin

Psiconáutica Editorial Team · October 8, 2026 In briefOn October 1, 2026, Canada’s new Controlled Substances Regulations went into effect, consolidating several previous rules into...

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Albert Hofmann and LSD: History of a Problem Child

From April 15 to 18 of this year, coinciding with the anniversary of Albert Hofmann’s discovery of LSD, a conference of psychedelic science experts organized by MAPS (http://www.maps.org) was held in San Jose, California. We will report on the event in detail in the print version of Cannabis Magazine. We are taking this opportunity to revisit some of the articles published in the magazine about the creator of LSD.

Albert Hofmann and LSD: Life and Legacy of the Swiss Chemist

Some individuals shape history, and Albert Hofmann was one of them. Without him, the 20th century would have been unrecognizable. Can we imagine it without psychopharmacology, the joyful—and sometimes wild—sixties, the hippies, psychedelic music, countercultural movements, alternative art, or substances like LSD and psilocybin? Our good doctor directly or indirectly influenced all those historical milestones that, in turn, continue to resonate today.

“Hemp as Biomass: Future Energy or Old Green Myth?”

Hemp seed contains around 30% oil. This oil has historically been used to produce high-grade diesel fuel oil and lubricants for aircraft engines and precision machinery. Throughout history, hemp seed oil has also been widely utilized as lamp oil.

Shulgin and MDMA: From Merck’s Archives to the Personal Lab

Shulgin’s intensity scale, the long oblivion of MDMA in Merck’s archives, and its 1965 rediscovery, stripped of sensationalism.

Wild Psychoactive Plants of the Iberian Peninsula (Part 1)

A botanical and critical overview of Iberian wild psychoactive plants: ephedra, opium poppy, wild lettuce, Syrian rue, and khat, with safety warnings.

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